Dr. Sergio Abonante Chirurgo Senologo

GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs) Introduction: Estrogens regulate critical signaling pathways involved in the control of cell proliferation and differentiation in reproductive and non-reproductive tissues Scarica l’articolo

G-Protein–Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells OBJECTIVES: Given the ability of atrazine to exert estrogen-like activity in cancer cells, we evaluated the potential of atrazine to signal through GPR30 in stimulating biological responses in cancer cells Scarica …

GPER, IGF-IR and EGFR transduction signalling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts Abstract: Zinc (Zn) is an essential trace mineral that contributes to the regulation of several cellular functions, however it may be also implicated in the progression of breast cancer through …

A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models INTRODUCTION: Breast cancer is the most frequent malignancy in women, and mortality of affected individuals is mainly caused by the development of metastatic processes (Siegel et al., 2012), whichis driven at least in part …