A calixpyrrole derivative acts as an antagonist to GPER

A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models

INTRODUCTION: Breast cancer is the most frequent malignancy in women, and mortality of affected individuals is mainly caused by the development of metastatic processes (Siegel et al., 2012), which
is driven at least in part by the tumor microenvironment (Schedin and Borges, 2009).

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