ResearchGate

GPER, IGF-IR and EGFR transduction signalling are involved in stimulatory effects of zinc

GPER, IGF-IR and EGFR transduction signalling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts Abstract: Zinc (Zn) is an essential trace mineral that contributes to the regulation of several cellular functions, however it may be also implicated in the progression of breast cancer through …

Leggi tutto

Breast Cancer and Venous Disease

Breast Cancer and Venous Disease: A Retrospective Cohort Study Breast cancer (BC) and chronic venous disease (CVD) are in some way related to hormonal effects, and often the clinical manifestations of CVD intersect with the clinical course of BC. This article describes the correlations between these clinical conditions. Scarica l’Articolo

Leggi tutto

miR-221 stimulates breast cancer cells and
cancer-associated fibroblasts

miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling Background: MicroRNA (miRNAs) are non-coding small RNA molecules that regulate gene expression by inhibiting the translation of target mRNAs. Among several dysregulated miRNAs in human cancer, the up-regulation of miR-221 has been associated with …

Leggi tutto